Abstract | OBJECTIVES: DESIGN: A randomized open label two group cross-over study. MATERIALS AND METHODS: RESULTS: Twenty-six patients were enrolled in the study. The mean serum phosphorous concentrations showed a declining trend with lanthanum carbonate (from pre- drug levels of 7.88 +/- 1.52 mg/dL-7.14 +/- 1.51 mg/dL) and calcium acetate (from pre- drug levels of 7.54 +/- 1.39 mg/dL-6.51 +/- 1.38 mg/dL). A statistically significant difference was seen when comparing the change in serum calcium produced by these drugs (P < 0.05). Serum calcium levels increased with calcium acetate (from pre- drug levels of 7.01 +/- 1.07-7.46 +/- 0.74 mg dL), while it decreased with lanthanum carbonate (from pre- drug levels 7.43 +/- 0.77-7.14 +/- 0.72 mg/dL). The incidence of adverse effects was greater with lanthanum carbonate. CONCLUSION:
|
Authors | P Thomas Scaria, Reneega Gangadhar, Ramdas Pisharody |
Journal | Indian journal of pharmacology
(Indian J Pharmacol)
Vol. 41
Issue 4
Pg. 187-91
(Aug 2009)
ISSN: 1998-3751 [Electronic] India |
PMID | 20523871
(Publication Type: Journal Article)
|