Proton magnetic resonance spectroscopy findings of hemangioblastoma.

Abstract

We report a case of proton magnetic resonance spectroscopy (MRS) of hemangioblastoma in a 56-yearold man with a history of hyperlipidemia who was suffering from an equilibrium disorder. Proton MRS revealed a high mobile lipids (Lip) peak between 0.9 and 1.4 ppm, which was compatible with histologically proven lipids in the tumor. No lactate peak was recognized. The creatine/phosphocreatine peak was low. Choline-containing compounds were increased. The N-acetylaspartate peak was absent, which indicated that the tumor is of nonneurogenic origin. Combined with the absence of the necrotic component on magnetic resonance imaging, this Lip peak on proton MRS could be the characteristic pattern of hemangioblastoma. These unique results of proton MRS can play an important role in the differential diagnosis of intracranial hemangioblastoma. However, further investigations are required to establish the typical characteristics of proton MRS of hemangioblastoma.

• Authors: Tomonori Isobe, Tetsuya Yamamoto, Hiroyoshi Akutsu, Izumi Anno, Masanari Shiigai, Alexander Zaboronok, Tomohiko Masumoto, Shingo Takano, Akira Matsumura
• Journal: Japanese journal of radiology (Jpn J Radiol) Vol. 28 Issue 4 Pg. 318-21 (May 2010) ISSN: 1867-108X [Electronic] Japan
• PMID: 20512552 (Publication Type: Case Reports, Journal Article)

Chemical References

• Protons

Topics

• Cerebellar Neoplasms (diagnosis, pathology, surgery)
• Diagnosis, Differential
• Hemangioblastoma (diagnosis, pathology, surgery)
• Humans
• Immunohistochemistry
• Magnetic Resonance Spectroscopy (methods)
• Male
• Middle Aged
• Protons