HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Motor cortex stimulation: functional magnetic resonance imaging-localized treatment for three sources of intractable facial pain.

Abstract
Neuropathic facial pain can be a debilitating condition characterized by stabbing, burning, dysesthetic sensation. With a large range of causes and types, including deafferentation, postherpetic, atypical, and idiopathic, both medicine and neurosurgery have struggled to find effective treatments that address this broad spectrum of facial pain. The authors report the use of motor cortex stimulation to alleviate 3 distinct conditions associated with intractable facial pain: trigeminal deafferentation pain following rhizotomy, deafferentation pain secondary to meningioma, and postherpetic neuralgia. Functional MR imaging was used to localize facial areas on the precentral gyrus prior to surgery. All 3 patients experienced long-lasting complete or near-complete resolution of pain following electrode implantation. Efficacy in pain reduction was achieved through variation of stimulation settings over the course of treatment, and it was assessed using the visual analog scale and narrative report. Surgical complications included moderate postsurgical incisional pain, transient cerebral edema, and intraoperative seizure. The authors' results affirm the efficacy and broaden the application of motor cortex stimulation to several forms of intractable facial pain.
AuthorsDarian R Esfahani, Marc T Pisansky, Rima M Dafer, Douglas E Anderson
JournalJournal of neurosurgery (J Neurosurg) Vol. 114 Issue 1 Pg. 189-95 (Jan 2011) ISSN: 1933-0693 [Electronic] United States
PMID20509733 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Adult
  • Aged, 80 and over
  • Electric Stimulation Therapy
  • Facial Pain (etiology, therapy)
  • Female
  • Herpes Zoster Oticus (complications)
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Meningeal Neoplasms (complications, surgery)
  • Meningioma (complications, surgery)
  • Middle Aged
  • Motor Cortex (pathology, physiopathology)
  • Myoclonic Cerebellar Dyssynergia
  • Pain, Intractable (etiology, therapy)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: