[Comparative evaluation of the effects of ethacizine and Bonnecor in the treatment of supraventricular paroxysmal tachycardia].

Abstract

The efficacy of ethacizine was investigated in 46 patients, whereas that of Bonnecor++ was examined in 31 patients who suffered from frequent episodes of supraventricular paroxysmal tachycardia. After intravenous administration of ethacizine and ++Bonnecor, tachycardia was sustained in 41 (89.1%) and 14 (45.0%) cases, respectively. Their arresting effect was observed in all 17 (100%) cases of nodal tachycardia and in 19 (82.6%) cases of orthodromic tachycardia. Moreover, the effect was obtained in 3 (75.0%) cases of antidromic tachycardia and in one case of atrial ectopic tachycardia. ++Bonnecor abolished an episode of nodal tachycardia only in 3 (23.0%) patients and that of orthodromic tachycardia in 9 (56.3%). Its effect was also seen in one case of antidromic tachycardia and in one case of atrial ectopic tachycardia. ++Anti-recurrence++ effects of ethacizine and ++Bonnecor in repeated episode provocation were seen in 26 (70.5%) and 10 (32.0%) cases, respectively. Side effects occurred more frequently when ethacizine was used.

• Authors: A I Lukoshiavichiute, D A Gedrimene, G Fol'kman
• Journal: Kardiologiia (Kardiologiia) Vol. 31 Issue 1 Pg. 67-70 (Jan 1991) ISSN: 0022-9040 [Print] Russia (Federation)
• Vernacular Title: Sravnitel'naia otsenka éffektivnosti étatsizina i bonekora pri lechenii nadzheludochkovoĭ paroksizmal'noĭ takhikardii.
• PMID: 2046254 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)

Chemical References

• Anti-Arrhythmia Agents
• Dibenzazepines
• Phenothiazines
• tiracizine
• ethacizine

Topics

• Adolescent
• Adult
• Aged
• Anti-Arrhythmia Agents (therapeutic use)
• Dibenzazepines (therapeutic use)
• Humans
• Middle Aged
• Phenothiazines (therapeutic use)
• Tachycardia, Paroxysmal (drug therapy)
• Tachycardia, Supraventricular (drug therapy)