A kidney tumor in an adolescent with severe hypertension and hypokalemia: an uncommon case--case report and review of the literature on reninoma.

Abstract

This report presents a case of a 16-year-old hypertensive boy who presented to our clinic. Laboratory findings showed severe hypokalemia and markedly increased plasma renin activity. Abdominal ultrasonography and contrast-enhanced computed tomography of the abdomen revealed a well-circumscribed, solid, hypoenhancing cortical lesion (2 cm) in the lower pole of the left kidney. The patient underwent nephron-sparing surgery. Histopathologic examination gave a diagnosis of juxtaglomerular cell tumor. Reninoma is an uncommon cause of hypertension in a young adult and should be included in the differential diagnosis as a potential life-threatening and curable condition. The conservative surgical management is the gold standard for small, circumscribed lesions.

• Authors: Fedra Gottardo, Maurizio Cesari, Aldo Morra, Marina Gardiman, Ambrogio Fassina, Massimo Dal Bianco
• Journal: Urologia internationalis (Urol Int) Vol. 85 Issue 1 Pg. 121-4 ( 2010) ISSN: 1423-0399 [Electronic] Switzerland
• PMID: 20453480 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: Copyright (c) 2010 S. Karger AG, Basel.

Chemical References

• Renin

Topics

• Adolescent
• Biopsy
• Humans
• Hypertension (blood, etiology)
• Hypokalemia (blood, etiology)
• Juxtaglomerular Apparatus (diagnostic imaging, metabolism, pathology, surgery)
• Kidney Neoplasms (blood, complications, diagnosis, surgery)
• Male
• Nephrectomy
• Renin (blood)
• Severity of Illness Index
• Tomography, X-Ray Computed
• Treatment Outcome
• Up-Regulation