[Research on substances with antiviral activity. VIII. Benzindanoncarboxylic acids].

Abstract	New derivatives (esters, amides, nitriles, amidines, thiosemicarbazones and guanylhydrazones) of 1H-benz[e]indene-2,3-dihydro-5-methyl-1-oxo-3-carboxylic acid and 1H-benz[e]indene-2,3-dihydro-7-methyl-3-oxo-1-carboxylic acid were prepared and tested for antiviral activities in vitro against vaccinia virus, HID stock and parainfluenza type 3 virus, HA-I/CR-8 stock. Four compounds (II g), (II i), (III b), (III g), showed weak activity in vitro against vaccinia virus.
Authors	V Cavrini, R Gatti, A Andreani, G Giovanninetti, L Franchi, A Nanetti
Journal	Il Farmaco; edizione scientifica (Farmaco Sci) Vol. 33 Issue 2 Pg. 92-8 (Feb 1978) ISSN: 0430-0920 [Print] Italy
Vernacular Title	Ricerche su sostanze ad attività antivirale. Nota VIII - Derivati di acidi benzindanoncarbossilici.
PMID	204512 (Publication Type: English Abstract, Journal Article)
Chemical References	Antiviral Agents Carboxylic Acids
Topics	Antiviral Agents (chemical synthesis) Carboxylic Acids (chemical synthesis, pharmacology) Chemical Phenomena Chemistry Research Respirovirus (drug effects) Vaccinia virus (drug effects)

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