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Translational medicine lessons from flurizan's failure in Alzheimer's disease (AD) trial: Implication for future drug discovery and development for AD.

AuthorsHong I Wan, J Steve Jacobsen, J Lynn Rutkowski, Giora Z Feuerstein
JournalClinical and translational science (Clin Transl Sci) Vol. 2 Issue 3 Pg. 242-7 (Jun 2009) ISSN: 1752-8062 [Electronic] United States
PMID20443898 (Publication Type: Journal Article, Comment)
Chemical References
  • Biomarkers
  • tarenflurbil
  • Flurbiprofen
Topics
  • Alzheimer Disease (drug therapy)
  • Animals
  • Biomarkers (metabolism)
  • Clinical Trials as Topic
  • Disease Progression
  • Drug Discovery
  • Flurbiprofen (pharmacokinetics, pharmacology, therapeutic use)
  • Humans
  • Patient Selection
  • Reproducibility of Results
  • Translational Research, Biomedical
  • Treatment Failure

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