Substance abuse and movement disorders.

Abstract

The complex relation between movement disorders and substance abuse is reviewed. First, we discuss the wide variety of movement disorders that occur as a direct consequence of acute use or withdrawal of drugs of abuse, such as alcohol, cocaine, heroin, amphetamine and methcathinone. Second, we describe the recent advances in the comorbid relationship between alcoholism and two movement disorders: essential tremor and myoclonus-dystonia. Lastly, we discuss the abuse potential of the dopaminergic agents, apomorphine and levodopa, in patients with Parkinson's disease.

• Authors: Marta San Luciano, Rachel Saunders-Pullman
• Journal: Current drug abuse reviews (Curr Drug Abuse Rev) Vol. 2 Issue 3 Pg. 273-8 (Sep 2009) ISSN: 1874-4745 [Electronic] United Arab Emirates
• PMID: 20443774 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Levodopa
• Apomorphine

Topics

• Alcoholism (complications)
• Animals
• Apomorphine (administration & dosage, adverse effects, therapeutic use)
• Humans
• Levodopa (administration & dosage, adverse effects, therapeutic use)
• Movement Disorders (etiology, physiopathology)
• Parkinson Disease (drug therapy)
• Substance Withdrawal Syndrome (physiopathology)
• Substance-Related Disorders (complications)