Abstract |
The epidemiological efficacy of 0.02 per cent solution of prodigiosan, a bacterial polysaccharide was used for the treatment of children in an area with acute respiratory infections, such as influenza and parainfluenza. The drug was administered intranasally by means of a dosing sprayer in the amounts of 0.2 ml once in 4 days for 4 months. Among the children treated with prodigiosan the rate of the acute respiratory viral infections was 2 times lower and the average duration of the disease was 2.4 times lower as compared to the control group. After 4 months of the drug use the average value of the "skin autoflora" test was much lower than that in the control group which testified to an increase in the non-specific immunobiological reactivity of the children under the effect of prodigiosan.
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Authors | O T Turgunbaev, L G Martynova |
Journal | Antibiotiki
(Antibiotiki)
Vol. 23
Issue 2
Pg. 183-5
(Feb 1978)
ISSN: 0003-5637 [Print] Russia (Federation) |
Vernacular Title | Primenenie prodigiozana dlia profilaktiki ostrykh respiratornykh virusnykh zabolevaniĭ v detskom kollektive. |
PMID | 204248
(Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Lipopolysaccharides
- Polysaccharides, Bacterial
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Topics |
- Acute Disease
- Administration, Intranasal
- Anti-Bacterial Agents
(therapeutic use)
- Child
- Clinical Trials as Topic
- Drug Evaluation
- Humans
- Influenza, Human
(prevention & control)
- Lipopolysaccharides
(therapeutic use)
- Paramyxoviridae Infections
(prevention & control)
- Polysaccharides, Bacterial
(therapeutic use)
- Respiratory Tract Infections
(prevention & control)
- Serratia marcescens
- Skin
(microbiology)
- Skin Tests
- Virus Diseases
(prevention & control)
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