[Use of prodigiozan for preventing acute respiratory viral diseases in a children's collective].

The epidemiological efficacy of 0.02 per cent solution of prodigiosan, a bacterial polysaccharide was used for the treatment of children in an area with acute respiratory infections, such as influenza and parainfluenza. The drug was administered intranasally by means of a dosing sprayer in the amounts of 0.2 ml once in 4 days for 4 months. Among the children treated with prodigiosan the rate of the acute respiratory viral infections was 2 times lower and the average duration of the disease was 2.4 times lower as compared to the control group. After 4 months of the drug use the average value of the "skin autoflora" test was much lower than that in the control group which testified to an increase in the non-specific immunobiological reactivity of the children under the effect of prodigiosan.
AuthorsO T Turgunbaev, L G Martynova
JournalAntibiotiki (Antibiotiki) Vol. 23 Issue 2 Pg. 183-5 (Feb 1978) ISSN: 0003-5637 [Print] USSR
Vernacular TitlePrimenenie prodigiozana dlia profilaktiki ostrykh respiratornykh virusnykh zabolevaniń≠ v detskom kollektive.
PMID204248 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Lipopolysaccharides
  • Polysaccharides, Bacterial
  • Acute Disease
  • Administration, Intranasal
  • Anti-Bacterial Agents (therapeutic use)
  • Child
  • Clinical Trials as Topic
  • Drug Evaluation
  • Humans
  • Influenza, Human (prevention & control)
  • Lipopolysaccharides (therapeutic use)
  • Paramyxoviridae Infections (prevention & control)
  • Polysaccharides, Bacterial (therapeutic use)
  • Respiratory Tract Infections (prevention & control)
  • Serratia marcescens
  • Skin (microbiology)
  • Skin Tests
  • Virus Diseases (prevention & control)

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