[Pediatric brain tumors--diagnostic and treatment].

Abstract

During the period 1995-2004 we treated 212 patients (pts) with brain tumors. There were 133 boys and 79 girls, aged from 2,5 yrs up to 18 yrs (Me = 9, 7 yrs). The majority of pts were in age group (4-16) yrs-179 pts. Supratentorial tumors were diagnosed in 118 pts vs. infratentorial 94 pts. Therapy involved surgery, postoperative radiotherapy with or without chemotherapy. Survival rates were calculated using Caplan-Meier method and differences between curves with log-rank test. During the follow-up period from 1 to 9 year (Me = 3 yrs) 5-year disease free survival rate was 55.7%. 79 pts failed to therapy. There was no statistically significant difference in survival according to sex (p = 0.123) and age (p = 0.367). Pts with supratentorial tumors had statistically significant better survival (p = 0.036). Pts with histologic type low grade astrocitomas had statistically significant better survival than malignant gliomas, ependymomas and PNET (p = 0.0001). Surgery, postoperative radiotherapy and chemotherapy in selected cases are efficient therapeutic approach for pediatric brain tumors.

• Authors: M R Nikitović, I V Golubicić, N D Borojević, T D Pekmezović, D M Grujicić, V S Plesinac-Karapandzić
• Journal: Acta chirurgica Iugoslavica (Acta Chir Iugosl) Vol. 56 Issue 4 Pg. 19-24 ( 2009) ISSN: 0354-950X [Print] Serbia
• PMID: 20419991 (Publication Type: English Abstract, Journal Article)

Topics

• Adolescent
• Brain Neoplasms (diagnosis, mortality, surgery)
• Child
• Child, Preschool
• Disease-Free Survival
• Female
• Humans
• Male
• Supratentorial Neoplasms (diagnosis, mortality, surgery)
• Survival Rate