Abstract | OBJECTIVE: This population-based study aimed to assess the relation between herpangina and adverse pregnancy outcomes: low birthweight (LBW), small for gestational age (SGA), and preterm delivery. STUDY DESIGN: A total of 242 pregnant women who had singleton births and who visited ambulatory care centers for the treatment of herpangina were assessed, together with 1936 matched women as a comparison group. Conditional logistic regression analyses were performed to examine the risk of LBW, preterm birth, and SGA for mothers with herpangina and unaffected mothers. RESULTS: Compared with pregnant women without herpangina, herpangina was associated with a 2.29- (95% confidence interval [CI], 1.42-3.69), 1.67- (95% CI, 1.04-2.68), and 1.63-fold (95% CI, 1.14-2.33) increased risk of having LBW, preterm, and SGA infants, respectively, after adjusting for family income and maternal and infant characteristics. CONCLUSION: Our findings highlight a significant potential risk posed by herpangina, a usually mild disease, among pregnant women.
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Authors | Yi-Hua Chen, Hsiu-Chen Lin, Herng-Ching Lin |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 203
Issue 1
Pg. 49.e1-7
(Jul 2010)
ISSN: 1097-6868 [Electronic] United States |
PMID | 20417474
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright (c) 2010 Mosby, Inc. All rights reserved. |
Topics |
- Adult
- Chi-Square Distribution
- Cohort Studies
- Enterovirus
(isolation & purification)
- Female
- Herpangina
(epidemiology, virology)
- Humans
- Infant, Low Birth Weight
- Infant, Newborn
- Infant, Small for Gestational Age
- Male
- Pregnancy
- Pregnancy Complications, Infectious
(epidemiology, virology)
- Premature Birth
- Taiwan
(epidemiology)
- Young Adult
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