Abstract | BACKGROUND AND OBJECTIVE: MATERIAL AND METHODS: Cells of the human gingival epithelial cell line Ca9-22 were cultured in media containing OxLDL, and the amounts of interleukin-8 (IL-8) and prostaglandin E(2) ( PGE(2)) produced were measured using ELISAs. RESULTS: CONCLUSION: This is the first report to show that OxLDL enhances IL-8 production in epithelial cells.
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Authors | K Suzuki, Y Sakiyama, M Usui, T Obama, R Kato, H Itabe, M Yamamoto |
Journal | Journal of periodontal research
(J Periodontal Res)
Vol. 45
Issue 4
Pg. 488-95
(Aug 2010)
ISSN: 1600-0765 [Electronic] United States |
PMID | 20412422
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- CCL2 protein, human
- CXCL8 protein, human
- Chemokine CCL2
- Enzyme Inhibitors
- Flavonoids
- Imidazoles
- Interleukin-1beta
- Interleukin-8
- Ketocholesterols
- Lipoproteins, LDL
- Polysaccharides
- Pyridines
- Receptors, Scavenger
- Sulfuric Acid Esters
- acetyl-LDL
- oxidized low density lipoprotein
- Fucose
- Dextran Sulfate
- fucoidan
- Cholesterol 7-alpha-Hydroxylase
- Mitogen-Activated Protein Kinases
- p38 Mitogen-Activated Protein Kinases
- Dinoprostone
- 7-ketocholesterol
- SB 203580
- 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole
- 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
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Topics |
- Cell Line, Tumor
- Chemokine CCL2
(analysis)
- Cholesterol 7-alpha-Hydroxylase
(antagonists & inhibitors)
- Dextran Sulfate
(pharmacology)
- Dinoprostone
(analysis)
- Enzyme Inhibitors
(pharmacology)
- Epithelial Cells
(drug effects)
- Flavonoids
(pharmacology)
- Fucose
(pharmacology)
- Gingiva
(cytology, drug effects)
- Humans
- Imidazoles
(pharmacology)
- Interleukin-1beta
(analysis, pharmacology)
- Interleukin-8
(analysis, antagonists & inhibitors, drug effects)
- Ketocholesterols
(pharmacology)
- Lipoproteins, LDL
(antagonists & inhibitors, pharmacology)
- Mitogen-Activated Protein Kinases
(antagonists & inhibitors)
- Oxidation-Reduction
- Periodontitis
(metabolism)
- Polysaccharides
(pharmacology)
- Pyridines
(pharmacology)
- Receptors, Scavenger
(antagonists & inhibitors)
- Sulfuric Acid Esters
(pharmacology)
- p38 Mitogen-Activated Protein Kinases
(antagonists & inhibitors)
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