[Effect of reamberin on the lipid spectrum of the liver mitochondria in experimental widespread purulent peritonitis].

Abstract

Lipid spectrum of liver mitochondria has been studied in a group of 46 Chinchilla rabbits with experimental widespread purulent peritonitis. It is established that the drug reamberin that contains succinic acid produces a positive effect on the protein spectrum of liver mitochondria under these conditions, which is manifested by a decrease in the content of lysophosphatidylcholine and increases the levels of polyglycerophosphatides and sphyngomyelin.

• Authors: V A Kosinets, S S Osochuk, N N Iarotskaia
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) Vol. 73 Issue 3 Pg. 31-4 (Mar 2010) ISSN: 0869-2092 [Print] Russia (Federation)
• PMID: 20408428 (Publication Type: English Abstract, Journal Article)

Chemical References

• Glycerophosphates
• Lysophospholipids
• Phosphatidylcholines
• Phosphatidylethanolamines
• Phospholipids
• Reamberin
• Sphingomyelins
• Succinates
• phosphatidylethanolamine
• polyglycerolphosphate
• Meglumine
• Cholesterol

Topics

• Animals
• Cholesterol (metabolism)
• Glycerophosphates (metabolism)
• Lysophospholipids (metabolism)
• Meglumine (analogs & derivatives, pharmacology, therapeutic use)
• Mitochondria, Liver (drug effects, metabolism)
• Mitochondrial Membranes (metabolism)
• Peritonitis (drug therapy, metabolism)
• Phosphatidylcholines (metabolism)
• Phosphatidylethanolamines (metabolism)
• Phospholipids (metabolism)
• Rabbits
• Sphingomyelins (metabolism)
• Succinates (pharmacology, therapeutic use)