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Infantile facial haemangioma and subclinical left ventricular dysfunction: the importance of z score in the diagnostic and therapeutic process.

Abstract
Large facial haemangiomas have a high rate of complications and can be associated with neurological, ophthalmological and cardiac abnormalities (PHACE syndrome; Posterior fossa malformations, Haemangiomas, Arterial anomalies, Coarctation of the aorta and cardiac defects, and Eye abnormalities). However, a thorough clinical examination is absolutely necessary. In fact, even in the absence of a PHACE syndrome, large haemangiomas can induce important complications. In the present brief report we describe a case of left ventricular dilatation in a 6-month-old girl due to a giant facial haemangioma. Left ventricular dilatation has been evaluated by two-dimensional echocardiography. Studies to identify other major arteriovenous malformations were negative. Medical therapy with diuretics, angiotensin-converting enzyme (ACE) inhibitors and steroids was able to halt the progression towards left ventricular dysfunction, avoiding an early surgical approach for a disease that very often is self-limiting.
AuthorsPasquale Cuccaro, Antonio Rapacciuolo, Renato Vitiello, Elisa di Pietro, Paolo Montaldo, Francesca Esposito, Gennaro Maresca, Antonio Correra
JournalJournal of cardiovascular medicine (Hagerstown, Md.) (J Cardiovasc Med (Hagerstown)) Vol. 11 Issue 9 Pg. 692-4 (Sep 2010) ISSN: 1558-2035 [Electronic] United States
PMID20404742 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Angiotensin-Converting Enzyme Inhibitors
  • Diuretics
  • Steroids
Topics
  • Angiotensin-Converting Enzyme Inhibitors (therapeutic use)
  • Dilatation, Pathologic
  • Diuretics (therapeutic use)
  • Facial Neoplasms (complications, physiopathology)
  • Female
  • Hemangioma (complications, physiopathology)
  • Hemodynamics
  • Humans
  • Infant
  • Steroids (therapeutic use)
  • Treatment Outcome
  • Ultrasonography
  • Ventricular Dysfunction, Left (diagnostic imaging, drug therapy, etiology, physiopathology)

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