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Effect of artrofoon on parameters of endogenous intoxication and activity of myeloperoxidase in leukocytes from patients with postoperative peritonitis.

Abstract
We studied the possibility of using artrofoon in the treatment of patients with localized suppurative postoperative appendicular peritonitis. A significant inhibiting effect of the preparation on endogenous intoxication parameters was demonstrated. Inhibition of myeloperoxidase hyperactivity is considered as a possible mechanism of the therapeutic effect of artrofoon as a component of complex therapy.
AuthorsA V Tarakanov, S L Luspekyan
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 148 Issue 3 Pg. 493-6 (Sep 2009) ISSN: 1573-8221 [Electronic] United States
PMID20396721 (Publication Type: Journal Article, Randomized Controlled Trial)
Chemical References
  • Antibodies, Monoclonal
  • Artrofoon
  • Peroxidase
Topics
  • Adolescent
  • Adult
  • Aged
  • Antibodies, Monoclonal (therapeutic use)
  • Enzyme Activation (drug effects)
  • Female
  • Humans
  • Leukocytes (enzymology)
  • Male
  • Middle Aged
  • Peritonitis (blood, drug therapy, enzymology)
  • Peroxidase (blood, metabolism)
  • Postoperative Period
  • Treatment Outcome
  • Young Adult

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