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Effectiveness and safety of balloon dilation of native aortic coarctation in premature neonates weighing < or = 2,500 grams.

Abstract
Six neonates weighing < or = 2,500 g with native coarctation of the aorta underwent balloon dilation. Of the 6 neonates, 4 were female and 2 were male, with a mean age of 14 days (range 9 to 20) and a mean weight of 1,900 g (range 790 to 2,500). The procedure was acutely successful in all 6 patients; the peak gradient decreased from 38 + or - 19 mm Hg to 11 + or - 3 mm Hg. The diameter increased from 1.5 + or - 0.6 mm to 3.6 + or - 0.7 mm. Of the 6 patients, 3 had required no additional intervention at a mean of 42 months after the initial dilation, and 3 had developed restenosis a mean of 2.4 months after the initial dilation and underwent successful redilation. Of the latter 3 patients, 2 developed restenosis and underwent surgical repair 37 and 68 days after the second dilation, and 1 of these patients developed recoarctation after surgery that was treated successfully with balloon dilation 54 days after the end-to-end repair. In conclusion, premature neonates weighing < or = 2,500 g with coarctation of the aorta appear to respond acutely to balloon dilation. Some patients will have a successful long-term result after a single balloon dilation procedure. However, restenosis is common and tends to develop rapidly.
AuthorsAbraham Rothman, Alvaro Galindo, William N Evans, Juan C Collazos, Humberto Restrepo
JournalThe American journal of cardiology (Am J Cardiol) Vol. 105 Issue 8 Pg. 1176-80 (Apr 15 2010) ISSN: 1879-1913 [Electronic] United States
PMID20381673 (Publication Type: Comparative Study, Journal Article)
CopyrightCopyright 2010 Elsevier Inc. All rights reserved.
Topics
  • Angiography
  • Angioplasty, Balloon (methods)
  • Aortic Coarctation (diagnosis, physiopathology, therapy)
  • Body Weight
  • Echocardiography, Doppler
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Infant, Premature
  • Male
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome

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