Usefulness of power Doppler ultrasonography and superparamagnetic iron oxide enhanced magnetic resonance imaging for diagnosis of focal nodular hyperplasia of the liver after treatment of neuroblastoma.

Abstract

Focal nodular hyperplasia (FNH) of the liver is rare in children, and it is usually diagnosed through a biopsy of the liver or hepatectomy. The authors report a case of a 10-year-old girl with multiple focal nodular hyperplasia lesions of the liver after the completion of tumor therapy for advanced neuroblastoma, and review the usefulness of the combination of power Doppler ultrasonography (US) and superparamagnetic iron oxide (SPIO) enhanced magnetic resonance imaging (MRI) for the diagnosis of FNH without a biopsy of the liver or hepatectomy.

• Authors: Kiminobu Sugito, Takeshi Kusafuka, Hiroyuki Kawashima, Shota Uekusa, Takeshi Furuya, Kensuke Ohashi, Mikiya Inoue, Taro Ikeda, Tsugumichi Koshinaga, Toshiya Maebayashi
• Journal: Pediatric hematology and oncology (Pediatr Hematol Oncol) Vol. 27 Issue 3 Pg. 250-6 (Apr 2010) ISSN: 1521-0669 [Electronic] England
• PMID: 20367270 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dextrans
• Magnetite Nanoparticles
• ferumoxides
• Ferrosoferric Oxide

Topics

• Child
• Dextrans
• Female
• Ferrosoferric Oxide
• Focal Nodular Hyperplasia (diagnosis)
• Humans
• Image Enhancement
• Magnetic Resonance Imaging (methods)
• Magnetite Nanoparticles
• Neuroblastoma (complications)
• Ultrasonography, Doppler (methods)