HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

The influence of socio-economic deprivation on rates of major lower limb amputation secondary to peripheral arterial disease.

AbstractOBJECTIVES:
To investigate a hypothesised link between socio-economic deprivation and rates of major lower limb amputation within the catchment of a district general hospital in the United Kingdom.
DESIGN:
An analysis of a demographic database collated using patients identified by the OPCS codes for lower limb amputations.
MATERIALS:
All patients undergoing a lower limb amputation as a result of peripheral vascular disease, as identified by ICD-10 code, between January 2003 and January 2009 were included in the study.
METHODS:
A case-control study was undertaken, comparing the Index of Multiple Deprivation 2007 (IMD) scores of major lower limb amputees, to those of the catchment population. Multivariate analysis was not undertaken.
RESULTS:
A total of 327 patients underwent 445 lower limb amputations during the 6-year period. A comparative plot of cumulative frequency of IMD score in the catchment and amputation groups indicates greater numbers of major amputations in more deprived postcodes (P=0.004). The catchment population was further divided into population-matched deprivation quintiles. A significant increase in the number of amputations occurred in the two most deprived quintiles (OR (95%CI)=1.654 (1.121-2.440), P=0.011)
CONCLUSIONS:
This study indicates a positive association between increasing social deprivation and rates of lower limb amputation. If the most deprived quintiles are combined, this increase in amputation rates is approximately 65%. This inequity should be further investigated, and consideration given to targeted care within areas of greater social deprivation.
AuthorsH J M Ferguson, P Nightingale, R Pathak, A P Jayatunga
JournalEuropean journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery (Eur J Vasc Endovasc Surg) Vol. 40 Issue 1 Pg. 76-80 (Jul 2010) ISSN: 1532-2165 [Electronic] England
PMID20362475 (Publication Type: Journal Article)
CopyrightCopyright 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.
Topics
  • Amputation, Surgical (statistics & numerical data)
  • Amputees (statistics & numerical data)
  • Case-Control Studies
  • Chi-Square Distribution
  • England (epidemiology)
  • Hospitals, District (statistics & numerical data)
  • Hospitals, General (statistics & numerical data)
  • Humans
  • Logistic Models
  • Lower Extremity (blood supply)
  • Odds Ratio
  • Patient Acceptance of Health Care
  • Peripheral Vascular Diseases (epidemiology, psychology, surgery)
  • Postal Service
  • Poverty Areas
  • Residence Characteristics (statistics & numerical data)
  • Risk Assessment
  • Risk Factors
  • Social Class
  • Socioeconomic Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: