[Lacrimal assessment of lg E in cases with allergic conjunctivitis].

Abstract

PURPOSE:

To present the study regarding Ig E tears dosation in cases with allergic conjunctivitis.

METHOD:

The Ig E tear dosation was done on two study groups--group A with 124 patients presenting allergic conjunctivitis symptoms (58 with seasonal allergic conjunctivitis, 43 with atopic allergic ocular symptoms, 23 treated with olopatadina 0.1% for 10 days) and compare group B consisting of 40 healthy patients (no local or general allergic symptoms) evaluated in the the Ophthalmology Clinic Arad between 2002-2008. The biological material used in the study was that of tears samples. For the determination of Ig E we used ELISA method, HUMAN IMUNO IG E QUANTITATION (Bethyl Laboratoires, Montgomery, TX) test.

RESULTS:

Significant statistic high levels of IgE concentration were observed in study group A in patients with allergic seasonal conjunctivitis (331.11 +/- 125.22 ng/ml) and patients with atopic terrain (177.18 +/- 56.70) compared to group B (67.25 +/- 8.89 ng/ml) with healthy patients. In the study group with allergic seasonal conjunctivitis there have been significant diminished IgE levels (71.70 +/- 9.94) after treatment.

CONCLUSION:

The method of IgE tears dosation proved to be efficient in establishing the ethiology of ocular allergies and in the screening of new cases with allergic conjunctivitis.

• Authors: Magdalena Turlea, D P Cioca, Flavia Mârza, C Turlea
• Journal: Oftalmologia (Bucharest, Romania : 1990) (Oftalmologia) Vol. 53 Issue 4 Pg. 96-100 ( 2009) ISSN: 1220-0875 [Print] Romania
• Vernacular Title: Dozarea Ig E in lacrimi la cazurile cu conjunctivită alergică.
• PMID: 20361659 (Publication Type: English Abstract, Journal Article)

Chemical References

• Biomarkers
• Immunoglobulin E

Topics

• Adolescent
• Adult
• Aged
• Algorithms
• Biomarkers (analysis)
• Case-Control Studies
• Child
• Conjunctivitis, Allergic (diagnosis, immunology)
• Enzyme-Linked Immunosorbent Assay
• Female
• Humans
• Immunoglobulin E (analysis, immunology)
• Lacrimal Apparatus (chemistry, immunology)
• Male
• Middle Aged
• Sensitivity and Specificity
• Tears (chemistry, immunology)