Screening of human brain tumors for SV40-related T antigen.

Abstract	A series of 39 human brain tumors has been screened for the presence or absence of SV40-related T antigen by the direct and indirect immunoperoxidase methods. Two tumors of ependymal origin (malignant ependymoma, choroid plexus papilloma) revealed markedly positive nuclear staining for T antigen both in vivo and in vitro. The relationship of these tumors to their experimental counterparts inducible by recent human papovavirus isolates is discussed.
Authors	K Tabuchi, W M Kirsch, M Low, D Gaskin, J Van Buskirk, S Maa
Journal	International journal of cancer (Int J Cancer) Vol. 21 Issue 1 Pg. 12-7 (Jan 15 1978) ISSN: 0020-7136 [Print] United States
PMID	203540 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References	Antigens, Viral
Topics	Antigens, Viral (analysis) Brain Neoplasms (immunology) Cerebral Ventricle Neoplasms (immunology) Choroid Plexus Complement Fixation Tests Fluorescent Antibody Technique Humans Immunoenzyme Techniques Male Middle Aged Simian virus 40 (immunology)

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