Abstract |
A case of solitary fibrous tumor (SFT) arising in the soft tissue of the left inguinal region is reported. A 57-year-old Japanese woman presented with a nonadherent, well-defined, oval mass that was 2 x 3 cm in diameter and located in the inguinal soft tissue. Microscopic evaluation showed proliferation of spindle-shaped, fibroblast-like cells by the coexistence of hypo- and hypercellular areas with mast cell infiltration separated by hemangiopericytoma-like blood vessels. Immunohistochemistry revealed strong expression of CD34 and CD99 in the fibroblast-like cells, supporting the diagnosis of SFT. Although the patient was free of symptoms such as hypoglycemia, immunoreactive insulin-like growth factor ( IGF)-II was localized in the socalled Golgi area of the spindle-shaped cells. In conclusion, immunoreactive IGF-II was detected in SFT that was not associated with hypoglycemia.
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Authors | Takashi Yuri, Sayaka Kanematsu, Yen-Chang Lei, Maki Kuwata, Masaharu Oishi, Airo Tsubura |
Journal | Medical molecular morphology
(Med Mol Morphol)
Vol. 43
Issue 1
Pg. 60-4
(Mar 2010)
ISSN: 1860-1499 [Electronic] Japan |
PMID | 20340008
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- 12E7 Antigen
- Antigens, CD
- Antigens, CD34
- CD99 protein, human
- Cell Adhesion Molecules
- Insulin-Like Growth Factor II
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Topics |
- 12E7 Antigen
- Abdominal Neoplasms
(chemistry, diagnosis, surgery)
- Antigens, CD
(analysis)
- Antigens, CD34
(analysis)
- Cell Adhesion Molecules
(analysis)
- Female
- Golgi Apparatus
(chemistry)
- Humans
- Hypoglycemia
(metabolism)
- Immunohistochemistry
- Inguinal Canal
- Insulin-Like Growth Factor II
(analysis)
- Middle Aged
- Solitary Fibrous Tumors
(chemistry, diagnosis, surgery)
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