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Mediastinal lymphangiomyoma in an adult: Report of a case.

Abstract
Lymphangiomyoma is a rare benign hamartoma of lymphatic origin. A 70-year-old woman presented with a 6-month history of a cough and dyspnea on exertion. Computed tomography and magnetic resonance imaging of the chest showed a 10 x 9 x 4 cm multiloculated tumor in the anterior mediastinum. We resected the tumor successfully, preserving all vital structures, even though the tumor margin was partially indistinct. The tumor was diagnosed as lymphangiomyoma based on the pathological and immunohistological findings. Hamartomatous lymphangiomyoma is not expressed by markers for secondary lymphangiomyoma of lymphangioleiomyoma, including human-melanoma-black-45 and progesterone receptor. The terminology and relevant literature on lymphangiomyoma are reviewed following this case report.
AuthorsHideki Ota, Yoshihiko Kimura, Hideki Kawai, Jun-ichi Ogawa
JournalSurgery today (Surg Today) Vol. 40 Issue 4 Pg. 365-8 (Apr 2010) ISSN: 1436-2813 [Electronic] Japan
PMID20339992 (Publication Type: Case Reports, Journal Article)
Topics
  • Aged
  • Female
  • Humans
  • Immunohistochemistry
  • Lymphangiomyoma (pathology)
  • Mediastinal Neoplasms (pathology)

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