Long-term outcomes of Oxane Hd as intraocular tamponade in the treatment of complicated retinal detachment.

Abstract

BACKGROUND:

To evaluate the efficacy and safety of heavy silicone oil Oxane Hd as intraocular tamponade in the treatment of complicated retinal detachment (RD).

METHODS:

Forty eyes of 40 patients with complicated RD were recruited for this prospective study. Inclusion criteria were proliferative vitreoretinopathy grade > or = CP2, mainly inferior and posterior retinal breaks, or superior retinal breaks with patient's inability to posture. Oxane Hd was used as intraocular tamponade. The retinal status, the best-corrected visual acuity (BCVA) results, and any complications were observed.

RESULTS:

The mean duration of Oxane Hd endotamponade was 87.9 +/- 10.4 days, and the mean follow-up time after Oxane Hd removal was 438.1 +/- 153.7 days. The primary anatomical success rate after Oxane Hd removal was 87.5%, and with further intervention 97.5%. The BCVA significantly improved, from mean logMAR 2.12 +/- 0.60 to 1.38 +/- 0.59 (P < 0.001). The postoperative complications included temporary inflammatory reaction, moderately high intraocular pressure, heavy silicone oil emulsification, lens opacity and retinal proliferative membranes.

CONCLUSIONS:

Without a requirement for postoperative prone position, heavy silicone oil Oxane Hd is effective and safe for the treatment of complicated RD with inferior and posterior breaks. Larger groups and a longer follow-up period will be included to further evaluate the efficacy with Oxane Hd in superior retinal breaks.

• Authors: Qianli Meng, Shaochong Zhang, He Cheng, Xuan Chen, Yixuan Jin
• Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (Graefes Arch Clin Exp Ophthalmol) Vol. 248 Issue 8 Pg. 1091-6 (Aug 2010) ISSN: 1435-702X [Electronic] Germany
• PMID: 20306070 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Emulsions
• Silicone Oils
• oxane HD

Topics

• Adult
• Aged
• Cataract (etiology)
• Combined Modality Therapy
• Drainage (methods)
• Emulsions
• Female
• Follow-Up Studies
• Humans
• Intraocular Pressure
• Laser Coagulation
• Male
• Middle Aged
• Postoperative Complications
• Prospective Studies
• Retinal Detachment (drug therapy, physiopathology, surgery)
• Retinal Perforations (drug therapy, physiopathology, surgery)
• Silicone Oils (adverse effects, therapeutic use)
• Treatment Outcome
• Visual Acuity (physiology)
• Vitrectomy (methods)
• Vitreoretinopathy, Proliferative (drug therapy, physiopathology, surgery)
• Young Adult