[Comparison of emepronium bromide with intravesical administration of lidocaine gel in women with urge incontinence].

Abstract

In the treatment of urge incontinence, drug therapy predominates. In a prospective randomised study on treatment of females with motor urge incontinence, intravesically administered lidocaine-gel and oral emepronium bromide were compared using clinical and urodynamic parameters. From 30 patients, 15 women were treated for 3 weeks with repeated intravesical lidocaine gel instillations whilst the other 15 had a peroral emepronium bromide medication. The intravesical lidocaine gel installation proved more efficient compared with peroral emepronium bromide therapy with regard to the parameters of imperative micturition, occurrence of detrusor contractions as well as number of urinary frequencies per diem. Intravesical application of lidocaine-gel is particularly indicated in patients with increased sensitivity against parasympathicolytics and anticholinergics.

• Authors: H Enzelsberger, C Schatten, C Kurz
• Journal: Geburtshilfe und Frauenheilkunde (Geburtshilfe Frauenheilkd) Vol. 51 Issue 1 Pg. 54-7 (Jan 1991) ISSN: 0016-5751 [Print] Germany
• Vernacular Title: Vergleich von Emeproniumbromid mit intravesikal appliziertem Lidocain-Gel bei Frauen mit Urge-Inkontinenz.
• PMID: 2026301 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Emepronium
• Lidocaine

Topics

• Administration, Intravesical
• Administration, Oral
• Emepronium (administration & dosage)
• Female
• Humans
• Lidocaine (administration & dosage)
• Middle Aged
• Urinary Incontinence (drug therapy)
• Urodynamics (drug effects)