[Intravaginal PgE2 administration for inducing labor in premature rupture of fetal membranes].

Abstract

In a prospective study, 121 patients with spontaneous rupture of the membranes of greater than 6 hours duration and unfavourable Bishop-Score (less than 6) were stimulated with 3 mg vaginal prostaglandin-E2-tablets. All patients started labour. Only one patient had a hyperstimulation which was corrected with betamimetics. There were no systemic side effects. Almost 90% of the women delivered on the first day. The rate of the Caesarean sections was low. There was no case of intraamniotic infection; the foetal outcome was good. In conclusion, vaginal prostaglandin-E2-tablets are safe to use in spontaneous rupture of the membranes.

• Authors: D Schaetti, D Blumer, N Dutar, R Gaudenz, W Hugentobler
• Journal: Geburtshilfe und Frauenheilkunde (Geburtshilfe Frauenheilkd) Vol. 51 Issue 1 Pg. 23-6 (Jan 1991) ISSN: 0016-5751 [Print] Germany
• Vernacular Title: Intravaginale Pg-E2-Gabe zur Geburtseinleitung bei vorzeitigem Blasensprung.
• PMID: 2026296 (Publication Type: English Abstract, Journal Article)

Chemical References

• Dinoprostone

Topics

• Administration, Intravaginal
• Cesarean Section
• Dinoprostone (administration & dosage)
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Female
• Fetal Membranes, Premature Rupture (therapy)
• Fetal Monitoring
• Humans
• Infant, Newborn
• Labor, Induced (methods)
• Pregnancy