Contribution of rearranged actin structures to the spread of Ectromelia virus infection in vitro.

Abstract	We describe here a contribution of virus-induced actin tails and filopodia in transmission of Ectromelia virus (ECTV) infection in permissive cells detected by the immunofluorescence and confocal microscopy. Immunoblot analysis revealed profoundly decreased beta-actin levels during ECTV replicative cycle in the infected cells 24 hrs post infection (p.i.). These results provided a basis for the further analysis of ECTV motion in the infected cells as well as for impact of ECTV infection on the cytoskeletal proteins.
Authors	A Boratynska, L Martyniszyn, L Szulc, M Krzyzowska, J Szczepanowska, M G Niemialtowski
Journal	Acta virologica (Acta Virol) Vol. 54 Issue 1 Pg. 41-8 ( 2010) ISSN: 0001-723X [Print] Slovakia
PMID	20201613 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Actins Cytoskeletal Proteins
Topics	Actins (metabolism, ultrastructure) Animals BALB 3T3 Cells (ultrastructure, virology) Chlorocebus aethiops Cytoskeletal Proteins (metabolism, ultrastructure) Ectromelia virus (pathogenicity, physiology) Ectromelia, Infectious (virology) Foot (virology) HeLa Cells (ultrastructure, virology) Humans Immunoblotting Mice Mice, Inbred BALB C Microscopy, Confocal Microscopy, Fluorescence Vero Cells (ultrastructure, virology)

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