[Successful pregnancy after 6 years complete remission in patient with acute myeloblastic leukemia].

Abstract

A 25-year-old woman was diagnosed as acute myeloblastic leukemia (M1 in FAB classification) in May 1983, and treated with DCMP regimen, which led to the complete remission. Intensification therapies and maintenance therapy with OK-432 were continued until August 1988, and 10 months later she conceived. She delivered a healthy 2,680 g male baby at 36th week of pregnancy by Cesarean section because of abruptio placentae. This case suggests that normal pregnancy is possible in patients with acute leukemia who received anti-cancer drugs.

• Authors: C Shimazaki, N Oku, H Gotoh, T Inaba, S Murakami, N Oku, K Itoh, S Nakanishi, M Nakagawa, N Fujita
• Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology (Rinsho Ketsueki) Vol. 32 Issue 1 Pg. 71-2 (Jan 1991) ISSN: 0485-1439 [Print] Japan
• PMID: 2020123 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cytarabine
• Prednisolone
• Mercaptopurine
• Daunorubicin

Topics

• Adult
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Cytarabine (administration & dosage)
• Daunorubicin (administration & dosage)
• Female
• Humans
• Leukemia, Myeloid, Acute (drug therapy)
• Mercaptopurine (administration & dosage)
• Prednisolone (administration & dosage)
• Pregnancy
• Remission Induction