Local hyperthermia at 44 degrees C for the treatment of plantar warts: a randomized, patient-blinded, placebo-controlled trial.

Abstract

There have been anecdotal reports that local hyperthermia was effective in the treatment of viral warts. We conducted a randomized, patient-blinded, placebo-controlled trial to test the effect of local hyperthermia (44 degrees C for 30 min a day for 3 consecutive days plus 2 additional days 2 weeks later) on plantar warts. By the end of 3 months, 53.57% of patients (15/28) in the treatment group and 11.54% of patients (3/26) in the control group were cured (P < .01). The effect was not influenced by patient age, duration of disease, or number or size of lesions.

• Authors: Wei Huo, Xing-Hua Gao, Xiu-Ping Sun, Rui-Qun Qi, Yuxiao Hong, Uwesu Omari Mchepange, Xiao-Dong Li, Bi-Huan Xiao, Jun-Ping Lin, Yi Jiang, Li Zhang, Yuan-Hong Li, Ting Xiao, John Z S Chen, Hong-Duo Chen
• Journal: The Journal of infectious diseases (J Infect Dis) Vol. 201 Issue 8 Pg. 1169-72 (Apr 15 2010) ISSN: 1537-6613 [Electronic] United States
• PMID: 20199243 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Topics

• Adolescent
• Adult
• Child
• Female
• Foot Dermatoses (therapy)
• Hot Temperature (therapeutic use)
• Humans
• Male
• Single-Blind Method
• Warts (therapy)
• Young Adult