Abstract | BACKGROUND AND OBJECTIVE: The purpose of the present study was to evaluate the effects of non-operative treatment using topical steroids on phimosis in infants and young children. MATERIAL AND METHOD: Between June 2003 and May 2005, the parents of the children with phimosis were instructed to apply and massage the phimotic skin with 0.05% betamethasone valerate cream twice daily for 2 months. During non-operative treatment, the patients whose parents were not satisfied with the results would undergo circumcision. RESULTS: Ninety-two phimotic boys with an average age of 32.62 months (range, 1 to 144 months) were enrolled for steroid application. Of the 92 patients, 79 (85.9%) were satisfied with their results. The other 13 patients whose outcomes clinically improved but did not satisfy their parents finally underwent circumcision. Histologically, circumcised skins of patients initially receiving steroid therapy revealed markedly interstitial edema and slightly increased vasculature. There were no systemic side effects or significant dermal atrophy in the present study. CONCLUSION: Topical steroid treatment for phimosis is successful in young children. This therapeutic approach is a safe, easy, and inexpensive alternative to circumcision.
|
Authors | Paiboon Sookpotarom, Suchat Porncharoenpong, Paisarn Vejchapipat |
Journal | Journal of the Medical Association of Thailand = Chotmaihet thangphaet
(J Med Assoc Thai)
Vol. 93
Issue 1
Pg. 77-83
(Jan 2010)
ISSN: 0125-2208 [Print] Thailand |
PMID | 20196415
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Anti-Inflammatory Agents
- betamethasone-17,21-dipropionate
- Betamethasone
|
Topics |
- Administration, Topical
- Analysis of Variance
- Anti-Inflammatory Agents
(administration & dosage)
- Betamethasone
(administration & dosage, analogs & derivatives)
- Child
- Child, Preschool
- Humans
- Infant
- Male
- Phimosis
(drug therapy)
- Treatment Outcome
|