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Hyaluronic acid binding and acrosin activity are decreased in sperm from men with spinal cord injury.

Abstract
In this study, acrosin activity and hyaluronic acid binding were compared in sperm from men with spinal cord injury versus sperm from healthy controls. The results showed statistically significantly lower acrosin activity and statistically significantly lower hyaluronic acid binding in spinal cord injured patients compared with controls, indicating functional impairments that may diminish the capacity of the sperm to fertilize oocytes.
AuthorsViacheslav Iremashvili, Nancy L Brackett, Emad Ibrahim, Teodoro C Aballa, Darren Bruck, Charles M Lynne
JournalFertility and sterility (Fertil Steril) Vol. 94 Issue 5 Pg. 1925-7 (Oct 2010) ISSN: 1556-5653 [Electronic] United States
PMID20188360 (Publication Type: Journal Article)
CopyrightCopyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Chemical References
  • Hyaluronic Acid
  • Acrosin
Topics
  • Acrosin (metabolism)
  • Adult
  • Case-Control Studies
  • Humans
  • Hyaluronic Acid (metabolism)
  • Infertility, Male (metabolism, physiopathology)
  • Male
  • Sperm Motility (physiology)
  • Sperm-Ovum Interactions (physiology)
  • Spermatozoa (metabolism)
  • Spinal Cord Injuries (metabolism)

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