Abstract | PURPOSE: METHODS: Review of the clinical findings of an 11.5-year-old boy with unilateral LSCD and epidermolysis bullosa dystrophica who underwent ocular surface reconstruction in the right eye with autologous on intact human amniotic membrane cultivated limbal epithelial cells. RESULTS: Twenty-eight months after reconstruction, the corneal surface is clear, smooth, and stable showing no signs of LSCD recurrence. Three subconjunctival bevacizumab ( Avastin) injections reduced the recurrent growth of symblepharon and corneal vascularization. The visual acuity has increased from hand motion to 20/50. CONCLUSION:
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Authors | Melissa Thanos, Mikk Pauklin, Klaus-P Steuhl, Daniel Meller |
Journal | Cornea
(Cornea)
Vol. 29
Issue 4
Pg. 462-4
(Apr 2010)
ISSN: 1536-4798 [Electronic] United States |
PMID | 20164760
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Cell Culture Techniques
- Child
- Corneal Diseases
(etiology, physiopathology, surgery)
- Epidermolysis Bullosa Dystrophica
(complications)
- Epithelial Cells
(physiology, transplantation)
- Epithelium, Corneal
(cytology, physiopathology)
- Humans
- Limbus Corneae
(cytology)
- Male
- Recovery of Function
- Stem Cell Transplantation
- Stem Cells
(pathology)
- Transplantation, Autologous
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