Atypical mycobacterium keratitis associated with penetrating keratoplasty: case report of successful therapy with topical gatifloxacin 0.3%.

To report successful therapy with gatifloxacin 0.3% ophthalmic solution (Zymar) in a patient with atypical mycobacterium keratitis after penetrating keratoplasty.
A 58-year-old patient was referred for evaluation of microbial keratitis after penetrating keratoplasty.
Clinical examination of the patient revealed an infiltrate at the inferior graft-host junction with a satellite lesion with a mild inflammatory reaction in the anterior chamber. Microbiologic evaluation confirmed the diagnosis of atypical mycobacteria keratitis. The corneal abscess was completely eradicated with a topical course of gatifloxacin 0.3% with preservation of graft clarity and good visual acuity. Topical treatment with gatifloxacin 0.3% was continued for an additional period of 5 months.
Topical gatifloxacin 0.3% may be successfully used to treat microbial keratitis resulting from atypical mycobacteria.
AuthorsAna Lilia Perez-Balbuena, Virginia Vanzzini-Zago, Manuel Garza, Diego Cuevas Cancino
JournalCornea (Cornea) Vol. 29 Issue 4 Pg. 468-70 (Apr 2010) ISSN: 1536-4798 [Electronic] United States
PMID20164758 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Infective Agents
  • Fluoroquinolones
  • gatifloxacin
  • Administration, Topical
  • Anti-Infective Agents (therapeutic use)
  • Corneal Ulcer (diagnosis, drug therapy, etiology)
  • Eye Infections, Bacterial (diagnosis, drug therapy, etiology)
  • Fluoroquinolones (therapeutic use)
  • Humans
  • Keratoplasty, Penetrating (adverse effects)
  • Male
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous (diagnosis, drug therapy, etiology)
  • Mycobacterium chelonae

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