Abstract | PURPOSE: To establish safe laser parameter standards for 10-30 ms Pascal(®) laser in clinical practice and to evaluate clinical and visual outcomes using this 532-nm multi-spot photocoagulation system. METHODS: Retrospective observational case series of 313 patients treated between 2006 and 2008. Evaluation of eight groups: A - panretinal photocoagulation (PRP) for proliferative diabetic retinopathy (PDR); B - focal laser treatment for clinically significant diabetic macular oedema; C - grid laser for diffuse diabetic macular oedema; D - sector PRP for ischaemic branch retinal vein occlusions (I-BRVO); E - full PRP for ischaemic central retinal vein occlusions (I-CRVO); F - macular laser treatment for macular oedema secondary to non-ischaemic BRVO; G - full PRP for rubeosis iridis and/or neovascular glaucoma (NVG) secondary to I-BRVO, I - CRVO or PDR; H - laser retinopexy for retinal breaks/degenerations. RESULTS: Mean LogMAR visual acuity for all procedures improved postlaser (p = 0.065), and laser prevented visual loss in 85% eyes. Topical anaesthesia was only required. At mean follow-up of 5 months, 72% procedures had a successful clinical outcome. Significantly higher powers were required for PRP using Pascal(®) compared to conventional laser (p = 0.001) in PDR, I-BRVO, I-CRVO and NVG. Sixty-seven per cent of patients (15/20) were successfully treated with single-session 20-ms PRP using a mean 1952 burns. There were no laser-associated adverse effects or ocular complications associated with multi-spot PRP or macular Pascal(®) arrays. CONCLUSIONS: The clinical efficacy using 10- to 30-ms pulse duration Pascal(®) laser is comparable to conventional standard protocols used for the treatment of vascular retinal disorders. Higher power, 10- to 30-ms pulse duration laser may be safely and effectively used in clinical practice.
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Authors | Mahiul M K Muqit, Chintan Sanghvi, Rita McLauchlan, Christine Delgado, Lorna B Young, Stephen J Charles, George R Marcellino, Paulo E Stanga |
Journal | Acta ophthalmologica
(Acta Ophthalmol)
Vol. 90
Issue 2
Pg. 155-61
(Mar 2012)
ISSN: 1755-3768 [Electronic] England |
PMID | 20163363
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2010 The Authors. Acta Ophthalmologica © 2010 Acta Ophthalmologica Scandinavica Foundation. |
Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Anesthesia, Local
- Blindness
(prevention & control)
- Female
- Fluorescein Angiography
- Follow-Up Studies
- Humans
- Laser Coagulation
(adverse effects, methods)
- Male
- Middle Aged
- Retinal Diseases
(physiopathology, surgery)
- Retinal Vessels
(physiopathology, surgery)
- Retrospective Studies
- Treatment Outcome
- Visual Acuity
(physiology)
- Young Adult
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