Benefits of examination by post mortem performed magnetic resonance imaging of foetus: haemorrhage in germinal matrix.

Abstract

Post mortem magnetic resonance imaging is demonstrated as a supplementary method to classic pathological-anatomical autopsy in determining anomalies of the foetus. Frequently it plays a key role; primarily where the possibilities of performing autopsy are somehow limited (autolysis, ventricular dilatation). Specification of the final diagnosis subsequently enables us to improve prenatal diagnostics, both by means of magnetic resonance imaging and primarily by correlation with the prenatal ultrasound scan; this feedback improves the later method. This case report demonstrated that post mortem magnetic resonance imaging, in contrast with prenatal ultrasound examination, showed extensive haemorrhage in the germinal matrix, and also illustrated indirect symptoms testifying to agenesis of the corpus callosum. Prenatal ultrasound examination showed only hydrocephalus and absence of septum pellucidum. Pathological-anatomical autopsy of the brain was insufficient with regard to advanced autolysis and brain haemorrhage.

• Authors: Manuela Vaneckova, Zdenek Seidl, Barbara Goldova, Ivana Vitkova, Pavel Calda
• Journal: Neuro endocrinology letters (Neuro Endocrinol Lett) Vol. 31 Issue 1 Pg. 40-2 ( 2010) ISSN: 0172-780X [Print] Sweden
• PMID: 20150878 (Publication Type: Case Reports, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Abnormalities, Multiple (diagnostic imaging)
• Aborted Fetus (diagnostic imaging)
• Acrocallosal Syndrome (diagnostic imaging, pathology)
• Adult
• Autopsy
• Blastodisc (diagnostic imaging, pathology)
• Cerebral Hemorrhage (diagnostic imaging, pathology)
• Diagnosis
• Female
• Humans
• Magnetic Resonance Imaging (methods)
• Predictive Value of Tests
• Pregnancy
• Radiography
• Ultrasonography