Effects of camel thorn distillate on recurrent oral aphthous lesions.

Abstract

BACKGROUND:

Near 20 % of people suffer from recurrent oral aphthous ulcers. These painful ulcers are found on the oral mucosa. We conducted this study to evaluate the effect of the camel thorn distillate on this condition.

PATIENTS AND METHODS:

93 patients with recurrent aphthous ulcers were selected and divided into two groups. One group was given a placebo (n = 44) and the other was given camel thorn distillate (n = 49). The diameter of the lesions and the severity of the pain were measured 3, 5, 7, 10 and 14 days after initiation of therapy. The lesion diameters and pain scores of the two groups were compared using the t-test.

RESULTS:

Complete resolution time ranged from 3 to 7 days (mean = 4.02) in the group treated with camel thorn distillate, whereas in the control group, complete resolution time ranged from 7 to 14 days (mean = 8.9, p < 0.001).

CONCLUSIONS:

The efficacy of camel thorn distillate is comparable to that of other drugs used to treat oral aphthous ulcers. Its therapeutic effect may be due to the flavanones (alhagitin and alhagidin) that are present in this plant.

• Authors: Morteza Pourahmad, Masood Rahiminejad, Sara Fadaei, Hamed Kashafi
• Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (J Dtsch Dermatol Ges) Vol. 8 Issue 5 Pg. 348-52 (May 2010) ISSN: 1610-0387 [Electronic] Germany
• PMID: 20136677 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Flavanones
• Glycosides
• Plant Extracts
• camel thorn distillate

Topics

• Adult
• Chronic Disease
• Double-Blind Method
• Female
• Flavanones (therapeutic use)
• Glycosides (therapeutic use)
• Humans
• Iran
• Male
• Middle Aged
• Phytotherapy
• Plant Extracts (therapeutic use)
• Secondary Prevention
• Stomatitis, Aphthous (drug therapy)
• Treatment Outcome