Abstract | OBJECTIVE: DESIGN: In this prospective, randomized, double-blind, drug-controlled trial,19 affected elbows of 16 patients were randomly assigned to receive injection with botulinum toxin type A ( Botox group) or triamcinolone acetonide ( steroid group). We used the Visual Analog Scale, pain-free grip strength, and World Health Organization Quality of Life Brief Questionnaire to assess the perception of pain, grip strength, and quality of life, respectively. Measures were performed before and at 4, 8, and 12 wks after the treatment. RESULTS: Four weeks after the treatment, the Botox group had smaller decrease in pain (P = 0.02) but greater decrease in grip strength (P = 0.01). The difference in grip strength remained significant at 8 wks (P = 0.03). No significant differences in quality of life were observed throughout the study period. CONCLUSIONS:
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Authors | Yu-Ching Lin, Yuan-Kun Tu, Sheng-Shiung Chen, I-Ling Lin, Shih-Ching Chen, How-Ran Guo |
Journal | American journal of physical medicine & rehabilitation
(Am J Phys Med Rehabil)
Vol. 89
Issue 8
Pg. 653-9
(Aug 2010)
ISSN: 1537-7385 [Electronic] United States |
PMID | 20134306
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Adrenal Cortex Hormones
- Neuromuscular Agents
- Botulinum Toxins, Type A
- Triamcinolone Acetonide
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Topics |
- Adrenal Cortex Hormones
(therapeutic use)
- Adult
- Botulinum Toxins, Type A
(therapeutic use)
- Double-Blind Method
- Female
- Hand Strength
- Humans
- Injections, Intra-Articular
- Male
- Middle Aged
- Muscle Weakness
- Neuromuscular Agents
(therapeutic use)
- Pain Measurement
- Pilot Projects
- Prospective Studies
- Tennis Elbow
(drug therapy)
- Triamcinolone Acetonide
(therapeutic use)
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