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A remorin protein interacts with symbiotic receptors and regulates bacterial infection.

Abstract
Remorin proteins have been hypothesized to play important roles during cellular signal transduction processes. Induction of some members of this multigene family has been reported during biotic interactions. However, no roles during host-bacteria interactions have been assigned to remorin proteins until now. We used root nodule symbiosis between Medicago truncatula and Sinorhizobium meliloti to study the roles of a remorin that is specifically induced during nodulation. Here we show that this oligomeric remorin protein attaches to the host plasma membrane surrounding the bacteria and controls infection and release of rhizobia into the host cytoplasm. It interacts with the core set of symbiotic receptors that are essential for perception of bacterial signaling molecules, and thus might represent a plant-specific scaffolding protein.
AuthorsBenoit Lefebvre, Ton Timmers, Malick Mbengue, Sandra Moreau, Christine Hervé, Katalin Tóth, Joana Bittencourt-Silvestre, Dörte Klaus, Laurent Deslandes, Laurence Godiard, Jeremy D Murray, Michael K Udvardi, Sylvain Raffaele, Sebastien Mongrand, Julie Cullimore, Pascal Gamas, Andreas Niebel, Thomas Ott
JournalProceedings of the National Academy of Sciences of the United States of America (Proc Natl Acad Sci U S A) Vol. 107 Issue 5 Pg. 2343-8 (Feb 02 2010) ISSN: 1091-6490 [Electronic] United States
PMID20133878 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Carrier Proteins
  • DNA Primers
  • Phosphoproteins
  • Plant Proteins
  • remorin
Topics
  • Base Sequence
  • Carrier Proteins (genetics, physiology)
  • DNA Primers (genetics)
  • Medicago truncatula (genetics, microbiology, physiology)
  • Molecular Sequence Data
  • Mutation
  • Phosphoproteins (genetics, physiology)
  • Plant Proteins (genetics, physiology)
  • Plants, Genetically Modified
  • RNA Interference
  • Rhizobium (genetics)
  • Signal Transduction
  • Sinorhizobium meliloti (physiology)
  • Symbiosis (physiology)
  • Transformation, Genetic

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