[Defibrillation efficacy of a newly developed automated external defibrillator in a swine ventricular tachycardia/fibrillation model].

Abstract

OBJECTIVE:

The aim of this study was to evaluate the recognition and defibrillation efficiency of a newly developed automated external defibrillator (AED).

METHOD:

Ventricular tachycardia (VT)/ventricular fibrillation (VF) was induced by alternating current (50 Hz) through an electrode placed on apex of right ventricle in 23 anesthetized swine and recorded, recognized and defibrillated by a newly developed AED.

RESULTS:

A total of 96 VF was induced and 145 defibrillations were recorded. We analyzed available 167 electrocardiosignal with a total length of 103,740 seconds. The accuracy, sensitivity and the specificity of the AED on VT/VF recognition are 99.5%, 98.2% and 99.6%, respectively. The success rate of defibrillation was 33.4% which increased in proportion to defibrillation energy. The defibrillation threshold of energy is 29.10-116.91 (78.75 +/- 35.64) J, the defibrillation threshold of electric quantity is (0.11 +/- 0.04) C and the defibrillation threshold of voltage is (1216.67 +/- 260.87) V.

CONCLUSIONS:

This newly developed AED has high sensitivity and the specificity on recognizing VT/VF. The lower success rate of defibrillation of this AED is associated with the low defibrillation energy during defibrillation which needs to be improved on further development.

• Authors: Jie Hui, Yun-Fei Gu, Xiao-Mei Wu, Zong-Cheng Zhu, Jian-Ping Song, Xiang-Jun Yang, Zhi-Hua Liu, Ting-Bo Jiang, Zu-Xiang Fagn, Wen-Ping Jiang
• Journal: Zhonghua xin xue guan bing za zhi (Zhonghua Xin Xue Guan Bing Za Zhi) Vol. 37 Issue 9 Pg. 845-8 (Sep 2009) ISSN: 0253-3758 [Print] China
• PMID: 20128387 (Publication Type: English Abstract, Journal Article)

Topics

• Animals
• Defibrillators
• Disease Models, Animal
• Electric Countershock
• Equipment Design
• Sensitivity and Specificity
• Swine
• Ventricular Fibrillation (therapy)