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Effect of absorbent tetracycline-loaded membrane used in the reduction of periodontal pockets: an in vivo study.

Abstract
This clinical study evaluated the influence of scaling and root planning (SRP), with and without the use of tetracycline-loaded bovine absorbent membrane, in the reduction of periodontal pockets according to 3 parameters: probing pocket depth (PPD), bleeding on probing (BOP) and plaque index (PI). Twenty-four patients were selected totalizing 144 random teeth divided in 2 groups (n=72 teeth) - control (SRP) and experimental (SRP with tetracycline-loaded absorbent membrane). PPD, BOP and PI were determined before and 28 days after the treatment. In all patients, the PPD values at the end of the treatment were always lower than the baseline values. There was a reduction of the PI for both treatments, but it was more evident on the experimental group. In conclusion, the use of tetracycline-loaded absorbent membrane could result in a better prognosis compared to scaling and root planning after only 28 days of evaluation.
AuthorsPriscilla Barbosa Ferreira Soares, Helder Henrique Machado de Menezes, Marina de Melo Naves, Eulázio Mikio Taga, Denildo de Magalhães
JournalBrazilian dental journal (Braz Dent J) Vol. 20 Issue 5 Pg. 414-8 ( 2009) ISSN: 1806-4760 [Electronic] Brazil
PMID20126911 (Publication Type: Journal Article, Randomized Controlled Trial)
Chemical References
  • Anti-Bacterial Agents
  • Membranes, Artificial
  • Tetracycline
Topics
  • Adult
  • Animals
  • Anti-Bacterial Agents (administration & dosage)
  • Cattle
  • Dental Plaque (prevention & control)
  • Dental Plaque Index
  • Dental Scaling
  • Drug Delivery Systems
  • Female
  • Humans
  • Male
  • Membranes, Artificial
  • Periodontal Index
  • Periodontal Pocket (drug therapy)
  • Tetracycline (administration & dosage)

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