Churg-Strauss syndrome versus chronic eosinophilic pneumonia on high-resolution computed tomographic findings.

Abstract

OBJECTIVES:

The aim of this study was to compare the high-resolution computed tomographic findings between Churg-Strauss syndrome (CSS) and chronic eosinophilic pneumonia (CEP).

METHODS:

We retrospectively reviewed the clinical records of 16 patients with CSS and 34 patients with CEP.

RESULTS:

Twelve (35%) of the 34 patients with CEP had a history of asthma. Although the subpleural distribution of ground-glass opacities (GGOs) and consolidation was common both in CSS and CEP, the midzone distribution was more frequent in CSS (44%) than in CEP (12%). Centrilobular nodules within GGOs were significantly more frequent in CSS (56%) than in CEP (18%). In contrast, traction bronchiectasis associated with volume loss was demonstrated more frequently in CEP (74%) than in CSS (25%).

CONCLUSIONS:

On high-resolution computed tomography, the presence of the midzone distribution and nodules within GGOs without traction bronchiectasis suggests CSS rather than CEP.

• Authors: Masashi Furuiye, Nobuyuki Yoshimura, Akiko Kobayashi, Meiyo Tamaoka, Yasunari Miyazaki, Yoshio Ohtani, Shuji Miyake, Naohiko Inase, Yasuyuki Yoshizawa
• Journal: Journal of computer assisted tomography (J Comput Assist Tomogr) Vol. 34 Issue 1 Pg. 19-22 (Jan 2010) ISSN: 1532-3145 [Electronic] United States
• PMID: 20118716 (Publication Type: Comparative Study, Journal Article)

Topics

• Chronic Disease
• Churg-Strauss Syndrome (diagnostic imaging)
• Diagnosis, Differential
• Female
• Humans
• Lung (diagnostic imaging)
• Male
• Middle Aged
• Pulmonary Eosinophilia (diagnostic imaging)
• Retrospective Studies
• Tomography, X-Ray Computed (methods)