HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Diagnosis and treatment of osteoporosis in persons aged more than 75 years].

Abstract
Osteoporosis is a progressive skeletal disease characterized by a decrease in bone strength and an increase in the number of fractures. This disease is considered by the World Health Organization to be the second most important health problem in the world after cardiovascular disease. The prevalence of osteoporosis is increasing due to population aging. With age, the loss of bone mass in the spine and hip, which starts at menopause in women and around the age of 60 years in men, continues. Old age is when most fragility fractures occur and the incidence of these fractures is increasing exponentially in persons aged more than 75 years. Several treatments with demonstrated effectiveness in decreasing fracture risk and increasing bone mineral density are currently available for osteoporosis. Nevertheless, the scientific evidence on the safety and efficacy of these treatments is much more scarce in older people than in young populations. There are few reports on the efficacy of these treatments in non-vertebral--specifically hip--fractures in the elderly. Consequently, the present review aims to analyze the scientific evidence on the diagnosis and treatment of osteoporosis, and particularly the evidence on the antifracture efficacy of distinct antiresorptive agents and anabolic drugs in people older than 75 years.
AuthorsMaría Jesús Moro-Alvarez, Manuel Díaz-Curiel
JournalRevista espanola de geriatria y gerontologia (Rev Esp Geriatr Gerontol) 2010 May-Jun Vol. 45 Issue 3 Pg. 141-9 ISSN: 0211-139X [Print] Spain
Vernacular TitleDiagnóstico y tratamiento de la osteoporosis en mayores de 75 años.
PMID20116136 (Publication Type: Journal Article, Review)
Copyright2009 SEGG. Published by Elsevier Espana. All rights reserved.
Chemical References
  • Bone Density Conservation Agents
  • Organometallic Compounds
  • Thiophenes
  • strontium ranelate
  • Teriparatide
  • Risedronic Acid
  • Etidronic Acid
  • Alendronate
Topics
  • Aged
  • Alendronate (therapeutic use)
  • Bone Density Conservation Agents (therapeutic use)
  • Etidronic Acid (analogs & derivatives, therapeutic use)
  • Female
  • Humans
  • Male
  • Organometallic Compounds (therapeutic use)
  • Osteoporosis (diagnosis, drug therapy)
  • Risedronic Acid
  • Teriparatide (therapeutic use)
  • Thiophenes (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: