[Is Cerebellar Soluble Lectin a major immunological target in multiple sclerosis?].

Abstract

In a recent paper: (Zanetta J.P. et al., Lancet, 1990, 335, 1482-1484) the authors showed that antibodies against the mannose-binding protein Cerebellar Soluble Lectin (CSL) are present in the cerebrospinal fluid of most multiple sclerosis patients. Herein, the properties and roles of the molecule as they are currently understood are described; hypotheses suggested by the consistent presence of anti-CSL antibodies in multiple sclerosis patients are discussed.

• Authors: J P Zanetta, J M Warter, S Lehmann, S Kuchler, G Vincendon
• Journal: Pathologie-biologie (Pathol Biol (Paris)) Vol. 39 Issue 1 Pg. 7-11 (Jan 1991) ISSN: 0369-8114 [Print] France
• Vernacular Title: La CSL (Cerebellar Soluble Lectin) joue-t-elle le rôle de cible immunologique privilégiée dans la sclérose en plaques?
• PMID: 2011413 (Publication Type: Editorial, English Abstract)

Chemical References

• Antibodies
• Lectins
• cerebellar soluble lectin

Topics

• Antibodies (analysis)
• Humans
• Immunologic Tests
• Lectins (analysis, immunology, physiology)
• Multiple Sclerosis (cerebrospinal fluid, immunology, physiopathology)