Abstract | BACKGROUND: OBJECTIVES: MATERIALS AND METHODS: In a split-face protocol, 10 patients were injected with Dermicol-P35 27G/topical anest:esia or Dermicol-P35 27G/0.3% lidocaine. Patients were monitored for adverse events and for pain using the Thermometer Pain Scale (TPS) and a visual analog scale (VAS). Efficacy was measured using the Modified Fitzpatrick Wrinkle Scale and the Global Aesthetic Improvement Scale. RESULTS: Patients experienced significantly less pain with Dermicol-P35 27G/0.3% lidocaine than with Dermicol-P35 27G/topical anesthesia (mean clinician-assessed TPS scores +/- standard deviation: 2.0 +/- 0.8 and 5.2 +/- 2.1, respectively, p<.001). Patients reported less discomfort with Dermicol-P35 27G/0.3% lidocaine than with Dermicol-P35 27G/topical anesthesia (mean VAS scores: 2.0 +/- 1.0 and 6.3 +/- 2.0, respectively, p<.001; TPS scores: 2.3 +/- 0.6 and 5.4 +/- 1.2, respectively, p<.001). Both treatments yielded similar efficacy scores and were well tolerated. Adverse events were mild. CONCLUSION:
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Authors | Susan Weinkle |
Journal | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
(Dermatol Surg)
Vol. 36
Issue 3
Pg. 316-20
(Mar 2010)
ISSN: 1524-4725 [Electronic] United States |
PMID | 20100268
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anesthetics, Local
- Drug Combinations
- dermicol-P35 27G
- Collagen
- Lidocaine
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Topics |
- Aged
- Anesthetics, Local
(administration & dosage)
- Collagen
(administration & dosage)
- Cosmetic Techniques
- Drug Combinations
- Face
(surgery)
- Female
- Humans
- Lidocaine
(administration & dosage)
- Male
- Middle Aged
- Pain, Postoperative
(prevention & control)
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