Abstract |
In our earlier experiments, we found that extremely low frequency magnetic fields (ELF-MF) affect heat shock protein (HSP) expression in wild type Escherichia coli cells. In the present work we investigate the ability of ELF-MF exposure to trigger an increase of DnaK and GroEL protein levels also in E. coli cells not exhibiting the classic heat shock response (HSR) when subjected to a 42 degrees C heat stress. We find that these cells, although lacking a HSR to heat shock treatment, show an enhancement of DnaK and GroEL protein levels after 30 or 90 min sinusoidal ELF-MF exposure (50 Hz, 1 mT). This result suggests that the HSP induction pathway triggered by ELF-MF exposure could be different from that elicited by heat shock treatment.
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Authors | Brunella Del Re, Pamela Marcantonio, Ferdinando Bersani, Gianfranco Giorgi |
Journal | General physiology and biophysics
(Gen Physiol Biophys)
Vol. 28
Issue 4
Pg. 420-4
(Dec 2009)
ISSN: 0231-5882 [Print] Slovakia |
PMID | 20097965
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Chaperonin 60
- Escherichia coli Proteins
- HSP70 Heat-Shock Proteins
- dnaK protein, E coli
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Topics |
- Chaperonin 60
(metabolism)
- Escherichia coli
(cytology, genetics, metabolism, physiology)
- Escherichia coli Proteins
(metabolism)
- Gene Expression Regulation, Bacterial
- HSP70 Heat-Shock Proteins
(metabolism)
- Heat-Shock Response
- Magnetics
- Temperature
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