Abstract | PURPOSE: MATERIALS AND METHODS: In this cross-sectional study urine and serum biochemistry was evaluated in 19 nonstone forming patients after Roux-en-Y gastric bypass and in 19 gender, age and body mass index matched obese controls without a history of nephrolithiasis. RESULTS: Compared with obese controls surgical patients had significantly higher mean +/- SD urine oxalate (45 +/- 21 vs 30 +/- 11 mg daily, p = 0.01) and lower urine citrate (358 +/- 357 vs 767 +/- 307 mg daily, p <0.01). The prevalence of hyperoxaluria (47% vs 10.5%, p = 0.02) and hypocitraturia (63% vs 5%, p <0.01) was significantly higher in surgical patients, who also had significantly lower urine calcium than obese controls (115 +/- 93 vs 196 +/- 123 mg daily, p = 0.03). The calcium oxalate urine relative supersaturation ratio was not significantly different between the 2 groups. CONCLUSIONS:
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Authors | Naim M Maalouf, Prasanthi Tondapu, Eve S Guth, Edward H Livingston, Khashayar Sakhaee |
Journal | The Journal of urology
(J Urol)
Vol. 183
Issue 3
Pg. 1026-30
(Mar 2010)
ISSN: 1527-3792 [Electronic] United States |
PMID | 20096421
(Publication Type: Journal Article, Research Support, N.I.H., Extramural)
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Copyright | 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Citric Acid
(urine)
- Cross-Sectional Studies
- Female
- Gastric Bypass
(adverse effects)
- Humans
- Hyperoxaluria
(epidemiology, etiology)
- Kidney Diseases
(epidemiology, etiology, urine)
- Male
- Middle Aged
- Nephrolithiasis
(etiology)
- Obesity
(complications)
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