HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Effect of joint laxity on polyethylene wear in total knee replacement.

Abstract
Experimental simulator studies are frequently performed to evaluate wear behavior in total knee replacement. It is vital that the simulation conditions match the physiological situation as closely as possible. To date, few experimental wear studies have examined the effects of joint laxity on wear and joint kinematics and the absence of the anterior cruciate ligament has not been sufficiently taken into account in simulator wear studies. The aim of this study was to investigate different ligament and soft tissue models with respect to wear and kinematics. A virtual soft tissue control system was used to simulate different motion restraints in a force-controlled knee wear simulator. The application of more realistic and sophisticated ligament models that considered the absence of anterior cruciate ligament lead to a significant increase in polyethylene wear (p=0.02) and joint kinematics (p<0.01). We recommend the use of more complex ligament models to appropriately simulate the function of the human knee joint and to evaluate the wear behavior of total knee replacements. A feasible simulation model is presented.
AuthorsJ Philippe Kretzer, Eike Jakubowitz, Robert Sonntag, Kerstin Hofmann, Christian Heisel, Marc Thomsen
JournalJournal of biomechanics (J Biomech) Vol. 43 Issue 6 Pg. 1092-6 (Apr 19 2010) ISSN: 1873-2380 [Electronic] United States
PMID20074735 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright 2009 Elsevier Ltd. All rights reserved.
Chemical References
  • Polyethylene
Topics
  • Anterior Cruciate Ligament (physiology)
  • Biomechanical Phenomena
  • Computer Simulation
  • Humans
  • In Vitro Techniques
  • Knee Joint (physiology)
  • Knee Prosthesis
  • Models, Biological
  • Movement
  • Nonlinear Dynamics
  • Polyethylene
  • Prosthesis Failure
  • Stress, Mechanical

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: