Percutaneous radionuclide ablation of axial aneurysmal bone cysts.

Abstract

OBJECTIVE:

The purpose of our study was to retrospectively examine the efficacy of intralesional injection of 32P chromic phosphate, a beta-emitting colloidal radiopharmaceutical, in the treatment of aneurysmal bone cysts of the axial skeleton. Five patients with large aneurysmal bone cysts were managed with injection of 32P chromic phosphate into their tumors under CT guidance. With only a single minor complication, all lesions were observed to ossify on follow-up CT, with an average follow up of 2 years.

CONCLUSION:

CT-guided injection of axial aneurysmal bone cysts with 32P chromic phosphate leads to excellent local lesion control. In addition, the morbidity associated with this procedure is lower than that associated with surgical or other nonsurgical treatments.

• Authors: Charles H Bush, Zachary Adler, Walter E Drane, Robert Tamurian, Mark T Scarborough, Charles P Gibbs
• Journal: AJR. American journal of roentgenology (AJR Am J Roentgenol) Vol. 194 Issue 1 Pg. W84-90 (Jan 2010) ISSN: 1546-3141 [Electronic] United States
• PMID: 20028896 (Publication Type: Journal Article)

Chemical References

• Chromium Compounds
• Phosphates
• Phosphorus Radioisotopes
• Radiopharmaceuticals
• chromic phosphate

Topics

• Adolescent
• Bone Cysts, Aneurysmal (diagnostic imaging, radiotherapy)
• Child
• Chromium Compounds (therapeutic use)
• Female
• Humans
• Injections, Intralesional
• Male
• Phosphates (therapeutic use)
• Phosphorus Radioisotopes (therapeutic use)
• Radiography, Interventional
• Radiopharmaceuticals (therapeutic use)
• Retrospective Studies
• Tomography, X-Ray Computed
• Treatment Outcome
• Young Adult