Abstract | OBJECTIVE: DESIGN: Thirty obese patients (3 M and 27 F) without MetS, 40 non-diabetic obese patients (3 M and 37 F) with MetS, and 30 controls (2 M and 28 F) were enrolled. METHODS: RESULTS: PON and arylesterase activities were similar between the groups, while TAS was low in both MetS and obese groups compared to controls (P<0.01 and P<0.05 respectively). CRP was higher in the MetS group compared with the obese and control groups (P<0.01 and P<0.001 respectively). In both the obese and MetS groups, CRP showed a positive correlation with body mass index (BMI). TAS was negatively correlated with BMI, waist circumference, triglyceride levels, and systolic and diastolic blood pressures (P<0.001). CONCLUSIONS: Oxidative stress is altered in non-diabetic MetS and non-MetS obese patients, but PON and arylesterase activities seem not to be affected. This result may be due to the absence of diabetes, the most severe form of altered carbohydrate metabolism.
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Authors | Suzan Tabur, Ayse Nur Torun, Tevfik Sabuncu, Mehmet Nuri Turan, Hakim Celik, Ali Riza Ocak, Nurten Aksoy |
Journal | European journal of endocrinology
(Eur J Endocrinol)
Vol. 162
Issue 3
Pg. 535-41
(Mar 2010)
ISSN: 1479-683X [Electronic] England |
PMID | 20022940
(Publication Type: Journal Article)
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Chemical References |
- Antioxidants
- Blood Glucose
- Lipids
- Carboxylic Ester Hydrolases
- arylesterase
- Aryldialkylphosphatase
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Topics |
- Adult
- Analysis of Variance
- Antioxidants
(metabolism)
- Aryldialkylphosphatase
(blood)
- Blood Glucose
(metabolism)
- Blood Pressure
(physiology)
- Body Mass Index
- Carboxylic Ester Hydrolases
(blood)
- Female
- Glucose Tolerance Test
- Humans
- Inflammation
(metabolism)
- Lipids
(blood)
- Male
- Metabolic Syndrome
(metabolism)
- Obesity
(metabolism)
- Oxidative Stress
(physiology)
- Regression Analysis
- Waist Circumference
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