Nonhemolytic Streptococcus pyogenes isolates that lack large regions of the sag operon mediating streptolysin S production.

Abstract

Among nonhemolytic Streptococcus pyogenes (group A streptococcus) strains (n = 9) isolated from patients with pharyngitis or acute otitis media, we identified three deletions in the region from the epf gene, encoding the extracellular matrix binding protein, to the sag operon, mediating streptolysin S production.

• Authors: Miho Yoshino, Somay Y Murayama, Katsuhiko Sunaoshi, Takeaki Wajima, Miki Takahashi, Junko Masaki, Iku Kurokawa, Kimiko Ubukata
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 48 Issue 2 Pg. 635-8 (Feb 2010) ISSN: 1098-660X [Electronic] United States
• PMID: 20018818 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Bacterial Proteins
• DNA, Bacterial
• Hemolysin Proteins
• Streptolysins
• streptolysin S

Topics

• Adult
• Bacterial Proteins (genetics)
• Child
• Child, Preschool
• DNA, Bacterial (chemistry, genetics)
• Female
• Hemolysin Proteins (biosynthesis)
• Humans
• Male
• Molecular Sequence Data
• Operon
• Otitis Media (microbiology)
• Pharyngitis (microbiology)
• Sequence Analysis, DNA
• Sequence Deletion
• Streptococcal Infections (microbiology)
• Streptococcus pyogenes (genetics, isolation & purification)
• Streptolysins (genetics)