Psychopathology in drug abusers and their families.

Abstract

Demographic, clinical, and family pedigree data obtained on 350 hospitalized drug-dependent patients showed that 52% also met DSM-III criteria for alcohol abuse or dependence, while 37% met DSM-III criteria for a concurrent axis I psychiatric disorder other than substance abuse. Cyclothymic disorder was significantly more common among cocaine abusers, while generalized anxiety disorder and panic disorder were more common among sedative-hypnotic abusers. Data on 1,478 first-degree relatives revealed that the prevalence of alcoholism and affective disorder was highly correlated with the occurrence of similar psychopathology in the probands. These findings suggest a relationship between drug of choice and comorbid psychopathology, a role for familial factors in the transmission of these disorders, and the importance of diagnostic subtypes in the evaluation and treatment of substance abusers.

• Authors: S M Mirin, R D Weiss, M L Griffin, J L Michael
• Journal: Comprehensive psychiatry (Compr Psychiatry) 1991 Jan-Feb Vol. 32 Issue 1 Pg. 36-51 ISSN: 0010-440X [Print] United States
• PMID: 2001619 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Hypnotics and Sedatives
• Cocaine

Topics

• Adult
• Alcoholism (genetics, psychology)
• Anxiety Disorders (genetics, psychology)
• Child of Impaired Parents (psychology)
• Cocaine
• Female
• Humans
• Hypnotics and Sedatives
• Male
• Mood Disorders (genetics, psychology)
• Opioid-Related Disorders (genetics, psychology, rehabilitation)
• Personality Inventory
• Psychiatric Status Rating Scales
• Risk Factors
• Substance-Related Disorders (genetics, psychology, rehabilitation)